Chevy big blocks have a long history with road racing. You just have to prepare the platform accordingly, and like UNGN said, a good helping of aluminum parts will get you straightened out.
I wish I got pictures of it but at our MSR track day I guy was restoring a BBC Hillborn injected 1970's Canam car. He didn't have the bodywork on it, but the monocoque was polished aluminum and the car looked amazing. He had just got it running and was testing the systems. It looked like $1 million and probably was.