R means radial-ply construction.
Speed rating. This letter denotes the maximum sustainable speed and is found directly after the load index. For S-speed-rated tires, it's 112 mph; for T, 118 mph. Speed ratings for other tires include Q, 99 mph; H, 130 mph; V, 149 mph; and Z, 150 mph plus. While such speeds may seem wildly impractical, tires with higher speed ratings tend to provide better handling at legal speed limits.