I've tuned a bunch of Q-Jets over the years, but never a 4.1. My primary tuning pieces are 69 thru 73 jets and 36 thru 44 rods. Your final combo will depend on any other mods you have made such as cam and exhaust, but I'd start with something like 70 jets and 42 rods. Drive it a bit, trying to accelerate as hard as possible while staying out of the secondaries. Lean out the jets until the acceleration gets a bit "stretchy", like its running out of fuel. Go a notch richer on the jets and then focus on the rods. Drive it again, paying close attention to your light to medium-throttle feel and response. What your looking for is crisp response. Too rich gets you slow initial response, but good pull after a second or two; Too lean gives you continued flat, lazy response.
When you get the primary metering dialed in, only then is it time to move to the secondaries. Once again you objective should be the same, crisp response and a steady pull. Maybe someone who's done the same carb on a similar engine will chime in and save you some steps, since I can't give you specifics. Carb tuning without a dyno is all seat-of-the pants feel, so be prepared to spend some time and effort in testing for best results. Give your float bowl gasket a good spray with silicone spray or WD-40 as you'll have the carb top off a multitude of times till you get it just right.
Bill