gbodyera said:The hose connection is tight.
Should there be any air hissing at all from the rad at any time? If I squeeze the hose i hear the air pushing out.
Only if the pressure exceeds what the cap is rated for. And then it would allow air or coolant to flow in to the overflow tank.
If you're sure the hose and/or connection isn't leaking then I would be looking strongly at the radiator itself. The next problem is if you have it full of coolant and start the car and get it up to temp, if there's a leak it will start leaking coolant. You may want to try to rent a cooling system pressure tester, it will allow you to pressurize the system and look for leaks.