They just have a hole cut in them for the factory door handle. As you can see, mine are black so I just taped off the chrome part of the handle and painted it black. I had thought about coming up with something else but it actually blends in pretty good and doesn't bother me like I thought it would.
The panels are made to order so you can get them with or without the holes for the door handles.
The panels are made to order so you can get them with or without the holes for the door handles.