carbs generally need to be retuned when you switch engine sizes. i'm assuming you went from a 307 or 350 to a 413? the greater air flow will pull more fuel, if the idle mixture screws don't do enough then you usually have to go into the carb. if it has an APT adjustment it might help at part throttle. as to the secondaries, remember that the flaps at the top are mostly controlled by air flow (and the flap movement is what controls fuel, not the lower flaps), so time adjustment is minimal. you can try to adjust the spring tension or the vac pull-off. changing the air valve shaft cam might also help as a smaller one would keep the rods farther into the jets, thus leaner. if you PM 85cutlassbrougham he can help more as he's played with them alot more than me and may know some tricks.
honestly, if you want the best performance out of it, pick up one of Cliff Ruggles books on rebuilding and modifying them. he now also sells kits and is a great guy to deal with. he'll help you to pick parts and calibrations/mods. it's not hard to do and the q-jet is a lot easier to work with than most people think.