I always like to ask what you intend to do with this when you are done? If this is a street cruiser, the amount of work required to get those power numbers out of a small block can be done but this motor will NOT have pleasant road manners. Now, if you are going live on the drag strip, then that is a different story.
Small blocks have to spin to make the kind of numbers you are seeking. This requires carburetor, intake, heads, and exhaust that will flow the air, and a really large cam and high lift capable valve train to feed it and then you need to spend money on the lower end to make it live at higher rpm ~ 7000 or so. If any piece of the airflow puzzle is off, your power production goes accordingly. When you are all done you may get there but the thing will have horrible street manners because you won't be getting into your power until about 3500rpm.
A mild big block gets you there yet maintains the pleasant street manners because it is there from 1500-5500. And, with an aluminum top end, you can build one that is actually a few pounds lighter than your small block. Just throwing that out there for consideration. Mine is a 442 so I wanted to get historical 442 type power numbers while maintaining streetability and even fuel efficiency. After spending literally years looking at all the options for the very limited 307, considering 350, 403, punching and stroking out a diesel block which I originally got my 425 crank to do, almost going with the [then] new Aurora-Caddy motor heavily modified, and even considered LS conversion for at least 10 minutes, I went big block Olds and have never regretted it.
Good information here:
http://www.442.com/oldsfaq/ofe350.htm#E350 350CIDEngineDetail
Sounds like an interesting project once you sort out the details but be realistic with what your goals for the car are going to be? I would MUCH rather have an efficient 300HP 350 on the street that is snappy quick with the right gears behind it even though there is always someone quicker than an over the top build that may get you to 425HP that has to idle at 1200-1500rpm and is generally pretty doggy and horribly wasteful literally dumping gas out the tail pipes until it comes to life just before the red lights are in your rear view mirror.
Good luck with it . . .