Greetings Ryanmjw & all; I've been playing around with Holley carbs since 1969 & I've learned enough to get myself into trouble. I've read your thread & I'll take a couple of shots. First double check your timing, I'm under the impression an Ls engine doesn't like very much? Second I feel that you may have the blades open too far for the idle circuit to work properly? As your idle screws aren't doing much! That's why I want you to check the timing. Next you may have a power valve failure, either check it or put in a new one. And make sure that it is at least 2 & up to 4 numbers below your idle vacuum. I also learned the hard way that Pro Form- Quick Fuel metering blocks want a very thick gasket (red from QF) on the power valve, as the threads don't seem to be as deep as on a Holley block. And last if you think how a power valve works, you soon understand why many do not run a secondary (rear) PV. As the fuel is pulled away from it under hard acceleration & it tends to go lean just when you want it to feed the main circuit, making tuning a problem. But when you plug or have no secondary PV you will need to jet the secondaries 6 to 10 #'s richer than the primary side. Keep in mind that the jets flow when you open the blades (possibly why your idle screws do little) & under full on the the PV opens to add extra fuel. You don't want that extra fuel under part throttle cruise (PV closed). So when you no longer have a secondary PV you have to add more jet to compensate for no PV flow. Good Luck, Ol'e Bob.
Ps: I usually call Quick Fuel about every other year with a new question, their tech line guys are very helpfull.