I don't believe piston speed is the issue. The increased rod to bore angle of a stroker is what accelerates wear IMHO.
But with the idea of it being a weekend warrior application, I would not be concerned about anything other than not running multiport fuel injection. The nitrous will cause more wear than the any stroker concerns. Nitrous and longevity.......not synonymous lol.
Confucious Nailhead say : the difference between nitrous and a turbo, you'll whip me to the 330' mark, and then I'll drive by like you have an anchor out back 🙂🙂
All kidding aside - to each his own - enjoy.