Keep your eye on the front suspension/steering components for wear. I think the key is to keep driving it and use everything on it. What I mean is keep using stufff like the HVAC system (AC/heat/vent) as that stuff can freeze up and not work properly if it is neglected. I'm pretty sure you'll have to tear the whole dash apart to try and fix anything if something does go wrong.
As long as the engine is in good shape after 20+ years and 100,000+ miles, there isn't any reason why it won't last 100,000 more. A lot of people say you have to replace timing chains at around 100,000 miles, as a failure would pretty much kill the engine. I've been trying to find out more about timing chain wear so I don't end up getting mine replaced for no reason, but I haven't had much luck. I guess there aren't any symptoms of wear.
Never let the car sit for extended periods of time without running it. I don't know a whole lot about engines, but from experience with similar cars, it is one of the worst things you can do. The fluids get gunky, etc. Plus, moisture gets into a dormant engine through the carburetor and exhaust and causes problems. Rings will get stuck, etc. The engine will start smoking/running rough and get bad gas mileage among other things.
Also, highway driving tends to be better for the car as well from what I have heard. Overall, DON'T beat on it, but don't putt around and carbon up the engine either.