ive never tried it personally. But ive been told the throttle body does depending on the year of the motor i think.
I know for a fact if your using truck accessories that you will have to move the idler pulley or else it will hit the throttle body. eBay has kits for like $30 to do that no biggy. The water neck on the truck water pump will also hit the big box on the drive by wire throttle body if you wanna remedy that you can use a camaro or vette water pump it moves that water neck away from the throttle body and you have to put 3/4 inch spacers behind the pump to line it up with the truck accessories. Or you could just use Fbody accessories period
As for fuel rails and stuff there is instructions on i think its ls1tech on how to use truck fuel rails and injectors on a ls6 intake. But personally i would just use ls1/ls6 rails with there injectors.