Greetings 39F & all; Since I haven't run a BB since the early 70's my advice could be dated?? For a reference, GM BB's with Holley's a 360 HP, 375 HP, 425 HP (L-72), 430 HP (L-88) & 450 - 465 HP. So lets look at the L-72 for starters. 780 CFM Vac secondary. What was the factory jetting? 70 Pri with 6.5 Pv & 76 Sec No PV. Next an L-88 had a 855 CFM Double Pump Pri 76 L - 72 R with a 6.5 Pv & the secondary 82 L - 78 R. They were cross jetted. If we go back to my oldest Holley book (late 60's) it states that if you're not running a rear PV 6 to 8 Jet sizes larger will be required to keep A/F mix balanced. My newer books say 8 to 10 jets sizes larger with no Pv. And from what I've learned the newer book is more accurate. Now your compression is less than all the previously mentioned engines as they were 11 to 1 & 12 to 1 examples with large rectangle port heads & solid lifter cams. So if ya want my opinion get a 750 or 780 Vac secondary Holley try 70 Pri with a 6.5 PV & 78 or79 Secondary jets without PV. The reason a don't want a secondary PV is as you accelerate fuel is pulled away from the metering block rendering the PV unreliable for consistent fuel flow. That's why secondary jets have extension on them (to pull fuel from the back end of the float bowl). Good luck Ole' Bob.