Take a look in your Summit catalog. They sell an 0.30 block already modded for 383. If you are building from scratch, start with a balanced rotating assembly, preferably forged stuff. Consider a 1-pc block:
http://www.summitracing.com/parts/sum-1 ... /overview/ This one is 4-bolt main, and has the setup for OEM roller lifters, but it does not have the fuel pump pad drilled. You can use hydraulic lifters at first, if you like. Talk to a machine shop that has experience with 383s...decide which is the better way to go, mod yours, or buy from Summit. Put your short block together with a 2-pc timing cover. You can upgrade heads and cam later.