the sealer flies further in the jambs because it's the heavier of everything your spraying.even heavier than high solids.I’ve been painting with PPG Envirobase for the past 4 years, in a shop where sealer is a necessary evil. The envirobase sealer is some of the best I’ve ever used and still
I prefer to paint over properly sanded primer over sealer any day. 9 times out of ten the job comes out much cleaner when there isn’t a coat of sealer. You also get sealer creep at your doorjambs. For some reason sealer goes in further than the base and clear.
You could always seal it, wait a long flash time, then nib sand it. I think the way you’re going over the car, your prep will be spot on and there’s no need to seal it.